The mesh nebuliser: a recent technical innovation for aerosol delivery

Randomised crossover trial of salbutamol aerosol delivered by metered dose inhaler, jet nebuliser, and ultrasonic nebuliser in chronic lung disease.

AIMS To compare the efficacy of salbutamol delivered by metered dose inhaler (MDI), jet nebuliser, and ultrasonic nebuliser in ventilated infants with chronic lung disease. METHODS Twenty preterm ventilated infants with chronic lung disease were enrolled in two studies. In study 1 (n = 10), each infant was given 200 micrograms of salbutamol at 4 hour intervals and in random sequence from a me...

Jet and ultrasonic nebuliser output: use of a new method for direct measurement of aerosol output.

Output from jet nebulisers is calibrated traditionally by weighing them before and after nebulisation, but the assumption that the weight difference is a close measure of aerosol generation could be invalidated by the concomitant process of evaporation. A method has been developed for measuring aerosol output directly by using a solute (fluoride) tracer and aerosol impaction, and this has been ...

Innovation in the Agro-Food Sector: from Technical Innovation-Centred Approaches to Sustainability Transition Processes

Innovation is a complex phenomenon and process involving translation of knowledge into new techniques, products, services. It is considered crucial for sustainable agriculture development and achievement of long-term food security. The review describes the diversity of innovation and relates it to agro-food sector. It also sheds light on different innovation models and explores their contributi...

A non-electrostatic spacer for aerosol delivery.

A pear shaped non-electrostatic spacer, composed of steel with a volume of 250 ml and equipped with a facemask containing integrated inlet and outlet valves for inspiration and expiration, was compared with three plastic spacers. The plastic spacers were primed with repeated puffs from a budesonide pressurised metered dose inhaler (p-MDI) to minimise the electrostatic charge on the plastic. The...

Revisiting the Relationship Between Systems of Innovation and Health Systems: A Response to Recent Commentaries